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Critical Care Medicines

Critical care medicine range comprises Buminate Injection, Invanz Injection, Zienem Injection, Actilyse Injection, Immunorel Injection, Vivem Injection, Gammaren Injection.

Human Albumin

Human Albumin

Generic Name:- Albumin

Albusor is fully compliant with Indian Pharmacopoeia . Our Albumin is coloured green because the briliverdin pigment bound to albumin does not removed when using the gentle chromatography method for purification .Since most manufacturers still use the old traditional cohn’s method of purification with harsh etanol treatment ,the albumin solution loses the bilirubin pigment , that would have got oxidised to biliverdin ,to give the green colour The traditional method used by other manufacturers is the cohn’s process of fractionation with etanol-which is an older technology with lesser yields and purity. As per European pharmacopeia, the specification for colour range to albumin solution ‘from greenish yellow to amber or green” .As long as the colour change is within the specification range considered acceptable. Albusor is prepared on new patented technology platform from which has three US patents granted . Albusor is developed using technology that involves an integrated end to end chromatography process for plasma proteins . In addition,two or more orthogonal steps are included in the manufacturing process for virus inactivation /removal . Albusor is formulated from plasma which is NAT Tested and negative for HIV-1,HIV-2,HBV and HCV. The beneficial effect of having bilirubin bound to Albumin is that it has a stabilising effect on Albumin. This is explained in detail in a presentation by CSL Bioplasma , Australia (available online).CSL also supplies a chromatographically purified Albumin (Albumex)that is green in colour and the anti –oxidative effects of bilirubin bound to albumin is explained in their product information slides.

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