Pazopanib
Types of Diseases:- Pazopanib is used to deal with some kinds of cancer (kidney, soft tissue sarcoma). Pazopanib fits in a category of drugs called as tyrosine kinase inhibitors. This medication functions by lowering the blood supply to the cancer tumor and sluggish tumor growth. Pazopanib ought to not be used by kids, particularly those younger than 2 years of age, owing to the possibility of serious side effects.
Uses:- Consume this medication orally with no food as instructed by your doctor, typically once daily. It is very crucial to pazopanib on an empty stomach, at least 1 hour earlier or 2 hours post taking food.
Swallow up this medication whole. Make sure not to crush, chew, or break down the tablets. Doing so can discharge all the drug at once, increasing the chance of side effects.
Avoid having grapefruit or sipping grapefruit juice while your ongoing treatment with this medication unless your doctor directs you else. Grapefruit can raise the possibility of side effects with this medication. Consult your doctor or pharmacist for further details.
Medications that decrease/prevent stomach acid (such as antacids, H2 blockers such as famotidine/ranitidine, proton pump inhibitors-PPIs such as omeprazole/lansoprazole) may decrease the assimilation of pazopanib, making it work less well. Do not consume tcH2 blockers or PPIs while using pazopanib. If you are having antacids, question your pharmacist about how to best take them, such as having antacids at least more than a few hours apart from when you have pazopanib. Speak with your doctor or pharmacist if you are taking any of these medications.
The dosage of pazopanib is centered on your medical condition, reaction to treatment, and other medicines you may be consuming. Ensure to inform your doctor or pharmacist regarding all the medications which you use (that comprises of prescription & non-prescriptions drugs, as well as herbal products).
Your doctor will ask for lab tests to know the best dose for you. Ensure to maintain all medical and lab appointments.
Most importantly, use these medicinal drugs consistently to reap the most benefit from it. To help you recall, consume it at the same time every day. However, do not raise your dose or consume pazopanib tablets more often or for extended period than prescribed. Your condition will not get better any faster, and your risk of grave side effects will simply escalate.
Since this drug can be immersed through the skin and lungs, women who are expecting or who may turn pregnant soon must not deal with this medication or respire the dust from the pazopanib tablets.
Side Effects:- Diarrhea, nausea or vomiting, head pain, loss of appetite, weight loss, changed sense of taste, lack of sensation/tingling/redness in hands/feet, or feeling tired/weak may be experienced. If these effects continue or deteriorate, speak to your doctor or pharmacist promptly.
Short-term hair loss and/or change in hair or skin color may arise. Normal hair growth must return after treatment has finished.
Let your doctor know right away if you are suffering from any grave side effects, comprising of: signs of heart failure (that includes swelling in ankles/feet, unfamiliar tiredness), symptoms of an underactive thyroid (that includes unexplained weight gain, sensitivity to cold, slow heartbeat), symptoms of infection (such as fever, chills, continuous sore throat, cough) and wounds that fail to heal.
Pazopanib can lead to severe (rarely fatal) bleeding. Speak to your doctor right away if you have any symptoms of strange bleeding such as: bloody/black stools, quick bleeding/bruising (that includes nosebleed or bloody/pinkish urine), vomit which seems like coffee grounds, serious stomach/abdominal pain, coughing up blood.
Pazopanib may raise your blood pressure. Examine your blood pressure consistently and tell your doctor if the outcomes are high. Your doctor may monitor your blood pressure with medication.
A very severe allergic reaction to this drug is uncommon. Though, get medical help straight away if you spot any symptoms of a severe allergic reaction, involving rash, itching/swelling (particularly of the face/tongue/throat), serious dizziness or trouble breathing.
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