Anti Cancer Injections

Bicnu Injection

Drug Name:- Carmustin

Strength : 100mg

Packing : Vial 

Type of Diseases : Various types of Cancer

Uses :- Bicnu Injection used in the treatment of several types of brain cancer including glioma, glioblastoma multiforme, medulloblastoma and astrocytoma), multiple myeloma and lymphoma Hodgkin's and non-Hodgkin, melanoma, lung cancer, colon cancer. Bicnu Injection is sometimes used in conjunction with alkyl guanine transferase (AGT) inhibitors, such as O6-benzylguanine The AGT-inhibitors increase the efficacy of Bicnu Injection by inhibiting the Direct Reversal pathway of DNA repair, which will prevent formation of the interstrand crosslink between the N1 of guanine and the N3 of cytosine It is also used as part of chemotherapeutic protocol to prepare for hematological stem cell transplantation, to reduce the white blood cells in the recipient (patient) This use under this protocol, usually with Fludarabine and Melphalan, was coined by oncologist at MD Anderson Cancer Center